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TOEIC・英語 大学生・専門学校生・社会人

解答を持ってなくノートにに書いたのがあっているのか不安なので皆さんの解答を参考にしたいです

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TOEIC・英語 大学生・専門学校生・社会人

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Abstract. In the present study, we investigated the effect of the Kampo medicme Yokukansan (YKS) on pentobarbital-induced sleep in group-housed and socially isolated mice. Socially isolated mice showed shorter sleeping time than the group-housed mice. YKS (300 mg/kg, p.o.) prolonged the pentobarbital-mduced sleeping time in socally isolated mice without affecting pentobarbtal sleep In group-housed mice. The prolongation of sleeping time by YKS was reversed by bcucul- Ine (3 mg/kg, ip.) and flumazenil (3 mg/kg, ip.), but not WAY100635. These findings suggest that the でABA。 - benzodiazepine receptor complex, but not 5-HTi。 receptors, 1s involved in the reversal effect of YKS on the decrease of pentobarbital sleep by socal isolation. eyの7の: sleep, soclal isolation, Yokukansan YKS), a Kampo medicine, is widely nia, Irritability, and screamng attacks. monstrated to improve behavioral and nptoms of dementia (BPSD), such as ltation, and irritability, in a randomized er, YKS improves sleep disturbance im ぐT) /う) 丁hnns 1c にak 人haf VIEKS bital-mduced sleep in group-housed and socially isolated mice. In addition, the 7?-aminobutyric acld。 (GABAA) benzodiazepine receptor complex is involved in the de- crease Of pentobarbital sleep by soclal isolation (7). Furthermore, social isolation influences でABAAreceptor subunit expression and postsynaptic serotonniA (5-HT」A) eneTfnr hinrhino in ncre (CS 9O) 征haerefnTe te alcn =eマamnュ=

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