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TOEIC・英語 大学生・専門学校生・社会人

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Abstract. In the present study, we investigated the effect of the Kampo medicme Yokukansan (YKS) on pentobarbital-induced sleep in group-housed and socially isolated mice. Socially isolated mice showed shorter sleeping time than the group-housed mice. YKS (300 mg/kg, p.o.) prolonged the pentobarbital-mduced sleeping time in socally isolated mice without affecting pentobarbtal sleep In group-housed mice. The prolongation of sleeping time by YKS was reversed by bcucul- Ine (3 mg/kg, ip.) and flumazenil (3 mg/kg, ip.), but not WAY100635. These findings suggest that the でABA。 - benzodiazepine receptor complex, but not 5-HTi。 receptors, 1s involved in the reversal effect of YKS on the decrease of pentobarbital sleep by socal isolation. eyの7の: sleep, soclal isolation, Yokukansan YKS), a Kampo medicine, is widely nia, Irritability, and screamng attacks. monstrated to improve behavioral and nptoms of dementia (BPSD), such as ltation, and irritability, in a randomized er, YKS improves sleep disturbance im ぐT) /う) 丁hnns 1c にak 人haf VIEKS bital-mduced sleep in group-housed and socially isolated mice. In addition, the 7?-aminobutyric acld。 (GABAA) benzodiazepine receptor complex is involved in the de- crease Of pentobarbital sleep by soclal isolation (7). Furthermore, social isolation influences でABAAreceptor subunit expression and postsynaptic serotonniA (5-HT」A) eneTfnr hinrhino in ncre (CS 9O) 征haerefnTe te alcn =eマamnュ=

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英語 中学生

下の写真で、赤線部のfive scientistとは、 黄線部の山中しんやさんと湯川ひできさんを含む4人のことですか。

内丈を読んで 設問に答えなさい。 Shinya Yamanake js 。 fumous scientist who *created *iPS cells- He *won *the Nobel Pe 2012 for his rearch、 and that was big wews。 Many people in Japan were ( ① ) and happy to hear the news. When Tomoko。 ahigh school stndent。 saw this news on TV。she became interested ip the Nobel Prize. She wanted to know more about Shinya Yamanaka、She found many stOHieS about him jn the newspapers. In one of the stories. a famous scientist said。 Shinya Yamanalka js young. He is only 50 years old. Ithink this news will give hope to othher young scientists Tomoko never thought a young scientist o) Hike Sbinya Yamanaka could win the Nobel Pe. She told her science teacher in school about this the next day. He 9) Xhear) her story and said,“There were four ( ③④ ) Japanese scientists who won the Nobel Prizes。 FThe youngest scientist won the Nobel Prize when he was 32 years old.” She thought that was wonderful and asked、 "Who was he?" “He was Hideki Yukawa。 There are some books about him ip the hibrary at our school TE you are interested in him。 go to the brary and study about る Hm waid her teacher。 "Tomoko knew only his name。She went to the ibrary and found some interesting stories about him by reading some books there。 生計 HHideki Yukawa was the Brst Japanese that won the prize、 ⑥ Tis mews gave Japanese people hope and made them very happy. EC

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