ページ1:

(chiral)
rotational (light) optically active
{lavorotary (-)
enantiomer same physical properties (F)-ES), different biological properties
Idextrorotatory (+) (optical isomer)
[X]D=
x
ex: 光偏轉 degree 同
(但方向反)
(receptors are also chiral)
dm
g/mL
chiral
chirality
achiral has a plane of symmetry
center
prochirality
absolute configuration
prochiral takes a chemical step to
sp²
or sp³
SR
用原子序排,e=0
become chiral
isomer
S
min 插入紙面
others 1-2-3
Stereoisomer:立体異構(原子連順序同,但空間排列不同)
enantiomer stereoisomer in which molecules + mirror image
Coptical isomer)
NIPIS...
tetrahedral is bonded to 4 different substituents
chirality center
diastereomer:非對映異構: not mirroringe:有些翻過去了,有些沒有R>S
epimer:表異構物:只有1個地方有翻 R↔S(是diastereomer 的一種)
constitutional
isomer
stereoisomer
enantiomer diastereomer
(mirror)
(non-mirror)
Conformer
Configural
cis-trans
meso compound : achiral but contain chirality centers: different physical properties
racemate/racemic mixture: 41: equal mixture of dextrorotatory & levorotatory forms
(±)/d, l
no optical rotation
n1 chirality center max: 2" 1 stereoisomer (JHE) A meso compounds
diastereomer
Not all molecules with chirality centers are chiral
overall - meso compounds are an exception

ページ2:

counterclockwise
+ substituent
for
prochirality
Re face
clockwise
Si face
prochirality center sp²
:
for
{pro-R atom's replacement leads to
R
pro-s:
S
• sp³ change I substituent
(enantiomers formed depend on which faces
undergo reactions)
→ chirality center
88
chirality center without affecting its priority with other attached groups
(pro R/S ES
方法)