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生物 高校生

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Test II PROBLEM SOLVING Directions: Answer the question and show your complete solution in the separate paper. 1. Suppose the cells lining of your cheeks can completely di vide every 24 hours. Assuming no cells die in the process, how many cheek cells will be there after 7 days if you started with 5 cheek cells? 2. If an organism has 15 pairs of homologous chromosomes, how many chromosomes will each daughter cell have after telophase of mitosis? Test I. Complete the concept in mitosis has the Cell division Purpose of which have occurs in through (10. condeneed which Includes or noncondensed which include 5。 温 a loop of DNA which Includes (in order) which form sister 9. during 12. (13. 14. which is followed by 15. which Is followed by (16. which includes (in order). 17. 19. >(20. What's New In meiosis the cell goes through similar stages in mitosis and uses similar strategies to organize and separate chromosomes. However, the cell has a more complex task in meiosis. It still needs to separate sister chromatids (the two halves of a duplicated chromosome), as in mitosis. But it must also separate homologous chromosomes, the similar but non-identical chromosome pairs an organism receives from its two parents. These goals are accomplished in meiosis using a two-step division process. Homologue pairs separate during a first round of cell division, called meiosis I. Sister chromatids separate during a second round, called meiosis III. Since cell division occurs twice during meiosis, one starting cell can produce four gametes (eggs or sperm). In each round of division, cells go through four stages: prophase, metaphase, anaphase, and telophase. Stages of Meiosis I In meiosis I, homologous chromosomes are separated into two cells such that there is one chromosome (consisting of

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生物 高校生

一塩基多型(SNP)は、資料集にのっているとおり病気へのかかりやすさなどが分かるというのは分かるのですが、ヒトの顔が違う、とかの違いはSNPに関係があるのですか? ネットで調べると 人と人とでは99.9%同じ配列だと書いてあったため、0.1%で人との違いが分かるのかなと思い... 続きを読む

3 ゲノム情報と医療 ゲノムの情報を利用して,個々人の体質に合わせて 一塩基多型(SNP) SNP (single nucleotide polymorphism) テーラーメイド医療 例 シトクロム P450 (CYP)と薬の投与量 ヒトA -AGACGGA- ·病気への かかりやすさ CYP CYP 一塩基置換 (SNP) · 薬の効き やすさ 野生型 変異型 ヒトB 副作用の 程度 酵素活性 通常 低い >-ATACGGA- 薬の投与量 多い 少ない シトクロム P450 (CYP)は薬の代謝に関 わる酵素で, SNP により酵素活性が異なる。 CYPのSNP 情報をもとに酵素活性を調べ ゲノムには,1つの塩基置換による個体差 ることで,個人に合った薬の投与量の推測 SNPの検出 DNAマイクロアレイ, 高速シークエンサー, PCR 薬の種類と量 の調節 病気の予防 医療の 流れ いちえんき たけい スニップ が存在し,これを一塩基多型 (SNP) とよぶ。が可能になるといわれている。 SNP の違いは,病気へのかかりやすさや, このように,SNP などのゲノムの個人 薬の効きやすさ,副作用の程度などに影響を 差に基づいた,個人の体質に合った病気の るCamScannerでスキャン 治療や予防が可能になると期待されている。 ※オーダーメイド医療ともよばれる。

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